CURRICULUM VITAE

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CURRICULUM VITAE Date: 10/30/2006 Name: Mark E. Sobel, M.D., Ph.D.

Date and Place of Birth: April 14, 1949; Brooklyn, New York

Citizenship: United States

Education:

1970 - B.A., Brandeis University 1975 - M.D., Mount Sinai School of Medicine 1975 - Ph.D. (Biomedical Sciences), City University of New York 1976 - Diplomate, National Board of Medical Examiners
Brief Chronology of Employment:
1971-1975 - Research Assistant, Department of Biochemistry, Mount Sinai School of
Medicine 1974-1975 - Lecturer, Biochemistry Clinical Correlates Course, Mount Sinai School
of Medicine 1975-1976 - Intern in Medicine, Children's Hospital Medical Center, Boston; Clinical
Fellow in Pediatrics, Harvard University 1976-1981 - Research Associate, Laboratory of Molecular Biology, National Cancer Institute, NIH 1979-1980 - Visiting Scientist, Department for Connective Tissue Research, Max
Planck Institute for Biochemistry, Martinsried bei Munchen, West
Germany 1981-1983 - Research Associate, Laboratory of Developmental Biology and
Anomalies, National Institute of Dental Research, NIH 1983-1992 - Senior Investigator, Laboratory of Pathology, National Cancer Institute,
NIH 1992-2001 - Chief, Molecular Pathology Section, Laboratory of Pathology, National
Cancer Institute, NIH 2001-2006 Guest Researcher, Laboratory of Pathology, NCI, NIH 2001-present Executive Officer, American Society for Investigative Pathology
2001-present Executive Officer, Association for Molecular Pathology
2001-present Managing Officer, Association of Pathology Chairs
2001-2002 Executive Officer, Universities Associated for Research and Education
in Pathology 2001-present Executive Officer, Intersociety Council for Pathology Information
2001-present Executive Officer, Association for Pathology Informatics
2001-present Executive Officer, International Society for Biological and Environmental Repositories 2006-present Executive Officer, Pulmonary Pathology Society
2006-present Special Volunteer, Laboratory of Pathology, NCI, NIH
Licensure (Medicine & Surgery):
#D20038 - Maryland #184977 - New York Mark E. Sobel, M.D., Ph.D.
CURRICULUM VITAE (Contd)
2
Uniformed Service:
1976-1983 - Surgeon, United States Public Health Service 1983-1990 - Senior Surgeon, United States Public Health Service 1990-2001 - Medical Director, United States Public Health Service
Societies: American Association for the Advancement of Science American Society for Investigative Pathology American Society for Biochemistry and Molecular Biology American Association for Cancer Research Association for Molecular Pathology
American Society of Association Executives
United States and Canadian Academy of Pathology
Honors and Awards:
1969 - Phi Beta Kappa, Brandeis University
1969 - John Leslie Award, Brandeis University
1970 - Summa cum laude, Brandeis University
1970 - Michael Bokat Award, Brandeis University 1975 - Basic Sciences Achievement Award, Mount Sinai School of Medicine
1977 - Sigma Xi
1989 - PHS Commendation Medal
1991 - Saul J. Horowitz, Jr. Memorial Award, Mount Sinai School of Medicine
1995 - Alpha Omega Alpha, Mount Sinai School of Medicine
2000- Highman Lecturer, University of California at Sacramento 2006- Leadership Award, Association for Molecular Pathology
Study Sections, Advisory Committees, Editorial Boards and Boards of Directors:
1981-1984 - Member, Study Section, Arthritis Foundation 1983-1985 - Associate Editor, Journal of Orthopaedic Research 1986-1991 - Editorial Board, Calcified Tissue International 1987 - Member, Minority Recruitment Networking Task Force, National
Cancer Institute 1988 - Member, Ad hoc, NIH Pathobiochemistry Study Section 1989 - Advisor, Programs Advisory Committee, NIDR 1989-2004 - Consultant, Molecular Pathology Committee, College of American Pathologists 1990-1995 - Chairman, Education Planning Committee, American Society for
Investigative Pathology 1991-1993 - Member, Long Range Planning Committee, American Association of
Pathologists 1991-1992 - Member, Research Grant Review Committee, American Cancer Society 1992-1998 - Member, Area Committee on Molecular Methods, National Committee
for Clinical Laboratory Standards Mark E. Sobel, M.D., Ph.D.
CURRICULUM VITAE (Contd)
3 Study Sections, Advisory Committees, Editorial Boards and Boards of Directors (contd):
1994 - Member, Organizing Committee, Molecular Diagnostics Workshop,
UAREP 1994-1995 - Director, Action Committee for the Association for Molecular Pathology 1994-1995 - Organizer, Stowell Symposium, Experimental Biology'95 Annual
Meeting 1995-1998 - Member, Editorial Board, Current Review of Pathology 1996 - Member, ad hoc, NIDR, Oral Cancer Center Study Section 1996-2000 - Associate Editor, Diagnostic Molecular Pathology 1966- Member, Advisory Committee on Informed Consent, NHLBI 1996-1999 - Member, Ad hoc Pathology Consensus on Stored Tissue Committee,
College of American Pathologists 1997-1998 - Chair, NIH Intramural Working Group on Studies Using Existing Human
Samples or Data 1998-present- Member, Editorial Board, Laboratory Investigation
1999-2001- Member, Ad hoc Committee on Genetics and Medical Information
Privacy, College of American Pathologists 1998-2001- Member, Trans-NIH Group on Issues Related to Human Specimen
Resources 1998-2001- Member, Trans-NIH Bioethics Committee 1999- Site Visitor, New York State Education Department 2000-2001- NIH Representative, DHHS Working Group on Use of Human
Biological Materials 2000-present Member, Editorial Board, Diagnostic Molecular Pathology
2000-2003 Member, Committee on Competency, American Board of Pathology 2001-present Board of Directors, Association for the Accreditation of Human Research Protection Programs 2002-2004 Member, Association of American Medical Colleges Council of
Academic Societies Program Committee 2002- Organizer and Moderator, Symposium on Molecular Surgical Pathology:
Studies in Wax, Annual Meeting of the United States and Canadian
Academy of Pathology 2003-2004 Organizer and Chair, Symposium on Human Research Protections,
Experimental Biology 2003 and 2004 2003-present Executive Committee, Association for the Accreditation of Human Research Protection Programs 2005-present Senior Executive Advisory Board, Archives of Pathology and Laboratory Medicine 2005- Member, Search Committee, Editor-in-Chief of FASEB Journal 2005-present Member, National Library of Medicine Working Group on the NIH Policy for Enhanced Public Access 2006-2007 Advisory Board, Washington G2 Reports Molecular Conference of 2007 2007- Member, PubMed Central National Advisory Committee of the National
Library of Medicine
Mark E. Sobel, M.D., Ph.D.
CURRICULUM VITAE (Contd)
4

Elected Offices:
1995-1997 - Councilor, American Society for Investigative Pathology 1995-1997 - Secretary-Treasurer, Association for Molecular Pathology 1997-1998 - Vice President-elect, American Society for Investigative Pathology 1998 - President-elect, Association for Molecular Pathology 1998-1999 - Vice President, American Society for Investigative Pathology 1999- President, Association for Molecular Pathology 1999-2000 - President, American Society for Investigative Pathology 2003-2006 - Chair, Intersociety Pathology Council
Teaching:
1986 - Lecturer, Extracellular Matrix Modulation of Cell Function, Catholic
University 1986 - Lecturer, Department of Biochemistry, Howard University 1987 - Co-director, Concepts in Molecular Biology Course, American
Association of Pathologists 1988- 1999 - Director, Concepts in Molecular Biology Course, American Society for Investigative Pathology 1991 - Organizer, Molecular Pathology Workshop, Annual Meeting of
Veterinary Pathologists 1994 - Faculty, University of Miami School of Medicine 19th Annual Review
and Recent Practical Advances in Pathology 1996 - Visiting Professor, Emory University School of Medicine 1997 - Visiting Professor, Ball Memorial Hospital, Muncie, Indiana 1998 Visiting Professor, Uniformed Services University of Health Sciences,
Veterinary Department 1999 2000 - Visiting Professor, George Washington University Medical School, Pathology Department 2002 - Course Director, Introduction to Molecular Biology, Annual Meeting of
the Society for Nuclear Medicine 2003- Visiting Professor, University of Miami School of Medicine 2004- Guest Lecturer, Medical College of Wisconsin 2005- Faculty, Current Applications of Molecular Pathology: Diagnosis and
Implications for Therapy in Tissue Samples, Madrid, Spain 2005- present Director, ASIP Journal Continuing Medical Education Program
Invited Keynote Lectures at National/International Meetings:
1985 - "Role of laminin receptor in metastasis," Annual Meeting of the Inter-American Society for Chemotherapy, Tampa, Florida 1986 - "Biochemical mechanisms of metastasis," Scientific Symposium of the 5th Anniversary of the Harrington Cancer Center, Amarillo, Texas 1987 - "Metastasis model systems," International Congress on Cancer Metastasis, Bologna, Italy Mark E. Sobel, M.D., Ph.D.
CURRICULUM VITAE (Contd)
5 Invited Keynote Lectures at National/International Meetings (contd):
1988 - "Introduction to molecular biology," VII Congress of the International Pediatric Nephrology Association, Toronto, Canada 1990 - "Genes for metastasis," US-Japan Breast Cancer Workshop, Osaka, Japan
1990 - "Genes that suppress metastatic potential," 32nd Annual Scientific Meeting of the American Society for Therapeutic Radiology and Oncology, Miami, Florida 1991 - Laminin receptors in metastasis," Basement Membrane Conference, Airlie, VA
1992 - "Introduction to molecular biology in pathological anatomy", Danish Society of Pathological Anatomy and Clinical Cytology Annual Meeting, Esjberg, Denmark 1992 - "Development and assessment of potentially new molecular markers in breast cancer metastasis," Pisa Symposium in Oncology, Pisa, Italy 1993 - "Molecular inhibitors of cancer invasion and metastasis," Cellular, Molecular and Clinical Aspects of Squamous Cell Carcinomas, Glasgow, Scotland 1993 - "Genetic and biochemical mediation of tumor invasion and metastasis," 4th Annual Symposium of the Yonsei Cancer Research Institute, Seoul, Korea 1995 - "Differential expression of mRNAs in human cancers," European Congress of Pathology, Copenhagen, Denmark 1995 - "Molecular biology for the clinician," Society for Nuclear Medicine, Annual Meeting, Minneapolis, MN 1996 - "Perspectives on informed consent for genetic research on stored tissue samples," Association for Molecular Pathology, Annual Meeting, Baltimore, MD 1997 - "Molecular biology for the clinician," Society for Nuclear Medicine, Annual Meeting, San Antonio, TX 1997 - "Ethical issues in clinical and research studies using human samples," Association for Molecular Pathology Annual Meeting, San Diego, CA 1998 Ethics of genetic testing: role of the clinical laboratory, American Association for Clinical Chemistry Eighth Annual Clinical Chemistry Forum, Crystal City,
VA 1999 - Ethical issues in molecular pathology: paradigms in flux, College of American Pathologists Conference XXXIV: Molecular Pathology: Role in Improving
Patient Outcome, Bethesda, MD 1999 - Ensuring Patient Privacy and Informed Consent in Histocompatibility Laboratories, American Society for Histocompatibility and Immunogenetics
Annual Meeting, New Orleans, LA 2000- Approaches to Developing Molecular Markers for Solid Tumors, University of California at Davis, Davis, CA 2001- Ethics of Genetic Testing in the Clinical Laboratory, Annual Beckman Conference, American Association for Clinical Chemistry, Newport Beach, CA 2001- The Protection of Participants (Human Subjects) in Research: Use of Biological Materials, ASCO/NCI Scientific Symposium on Molecular Oncology for the
Clinical Oncologist 2002- Repositories in Clinical and Genetic Research, University of Washington Symposium on Clinical Research 2002- Pharmacogenomics: Ethical and Social Issues, AACC Conference on Pharmacogenomics 2002- Ethical Considerations in Molecular Diagnostics and Therapeutics, IBC Conference on The Interface: Molecular Diagnostics Meets Therapeutics Mark E. Sobel, M.D., Ph.D.
CURRICULUM VITAE (Contd)
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Invited Keynote Lectures at National/International Meetings (contd):
2002- The Protection of Participants (Human Subjects) in Research: Use of Biological Materials, ASCO/NCI Scientific Symposium on Molecular Oncology for the
Clinical Oncologist 2002- Molecular Medicine in the Information Age: Ethical, Legal and Social Implications for Health Care in the 21 st Century, Conferenza Nazionale sulle Biotecnologie e Presentazione dellMGM, Istituto di Medicina e Genetica
Molecolare 2003- SNPs and Chips: The Future of Molecular Pathology in the Information Age, Southeast Association of Pathology Chairs Meeting, Key Biscayne, FL 2003- SNPs and Chips: The Future of Pathology Practice and Research in the Information Age, University of Toronto, Toronto, Canada 2004- The importance of tissue banking and tissue research, Conflicts of Interest, Privacy/Confidentiality, and Tissue Repositories, Boston, MA 2004- The Power of Molecular Biological Techniques, Experimental Biology 2004, Washington, DC 2004- Clinical impact of proteomics in surgical pathology of solid tumors, USCAP Annual Meeting, Vancouver, BC, Canada 2004- Patenting, licensing, and universities: trends and implications, National Academy of Sciences, Washington, DC 2005- Armed Forces Institute of Pathology Repository, Conference on the Future of the AFIP, Washington, DC 2005- Technical and ethical approaches to molecular pathology: diagnosis, prognosis and implications for therapy, Madrid, Spain
Patents:
Sobel et al: Recombinant DNA Clone Encoding Laminin Receptor Patent #4,861,710;
granted August 29, 1989
Steeg et al: Diagnosis of Metastatic Potential of Tumors by the NM23 gene #5,049,662;
granted September 17, 1991
Contact Information:
ASIP, 9650 Rockville Pike, Bethesda, MD 20814 Tel: 301-634-7130 Fax: 301-634-7990 Email: mesobel@asip.org

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